Targeting High Dynamin-2 (DNM2) Expression by Restoring Ikaros Function in Acute Lymphoblastic Leukemia

Dynamin-2 (DNM2) is a GTPase essential for intracellular vesicle formation and trafficking, cytokinesis and receptor endocytosis. Mutations in DNM2 are common in early T-cell precursor acute lymphoblastic leukemia. However, DNM2 expression in other types of ALL are not reported. We studied DNM2 mRNA...

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Detalles Bibliográficos
Autores principales: Ge, Zheng, Gu, Yan, Han, Qi, Zhao, Gang, Li, Min, Li, Jianyong, Chen, Baoan, Sun, Tianyu, Dovat, Sinisa, Gale, Robert Peter, Song, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122860/
https://www.ncbi.nlm.nih.gov/pubmed/27885263
http://dx.doi.org/10.1038/srep38004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122860/
https://www.ncbi.nlm.nih.gov/pubmed/27885263
http://dx.doi.org/10.1038/srep38004

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