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A holistic approach to dissecting SPARC family protein complexity reveals FSTL-1 as an inhibitor of pancreatic cancer cell growth

SPARC is a matricellular protein that is involved in both pancreatic cancer and diabetes. It belongs to a wider family of proteins that share structural and functional similarities. Relatively little is known about this extended family, but evidence of regulatory interactions suggests the importance...

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Detalles Bibliográficos
Autores principales: Viloria, Katrina, Munasinghe, Amanda, Asher, Sharan, Bogyere, Roberto, Jones, Lucy, Hill, Natasha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122892/
https://www.ncbi.nlm.nih.gov/pubmed/27886258
http://dx.doi.org/10.1038/srep37839