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mTOR regulates neuroprotective effect of immunized CD4+Foxp3+ T cells in optic nerve ischemia

The therapeutic potential of targeting CD4+Foxp3+ regulatory T cells (Tregs) remains controversial under the condition of neuroinflammation. This study aims to explore the neuroprotective role of Tregs in optic nerve ischemia (ONI) and evaluate the therapeutic strategy of Tregs transfer with a focus...

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Detalles Bibliográficos
Autores principales: Chen, Guochun, Tang, Luosheng, Wei, Wei, Li, Zhuo, Li, Yunping, Duan, Xuanchu, Chen, Huihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122903/
https://www.ncbi.nlm.nih.gov/pubmed/27886260
http://dx.doi.org/10.1038/srep37805