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Unlocking sperm chromatin at fertilization requires a dedicated egg thioredoxin in Drosophila

In most animals, the extreme compaction of sperm DNA is achieved after the massive replacement of histones with sperm nuclear basic proteins (SNBPs), such as protamines. In some species, the ultracompact sperm chromatin is stabilized by a network of disulfide bonds connecting cysteine residues prese...

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Detalles Bibliográficos
Autores principales: Tirmarche, Samantha, Kimura, Shuhei, Dubruille, Raphaëlle, Horard, Béatrice, Loppin, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122968/
https://www.ncbi.nlm.nih.gov/pubmed/27876811
http://dx.doi.org/10.1038/ncomms13539