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Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP

Little is known about how archaeal viruses perturb the transcription machinery of their hosts. Here we provide the first example of an archaeo-viral transcription factor that directly targets the host RNA polymerase (RNAP) and efficiently represses its activity. ORF145 from the temperate Acidianus t...

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Detalles Bibliográficos
Autores principales: Sheppard, Carol, Blombach, Fabian, Belsom, Adam, Schulz, Sarah, Daviter, Tina, Smollett, Katherine, Mahieu, Emilie, Erdmann, Susanne, Tinnefeld, Philip, Garrett, Roger, Grohmann, Dina, Rappsilber, Juri, Werner, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123050/
https://www.ncbi.nlm.nih.gov/pubmed/27882920
http://dx.doi.org/10.1038/ncomms13595