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Selective beneficial cardiometabolic effects of vertical sleeve gastrectomy are predominantly mediated through glucagon-like peptide (GLP-1) in Zucker diabetic fatty rats

BACKGROUND: Glucagon-like peptide-1 (GLP-1) level was significantly increased post Vertical Sleeve Gastrectomy (VSG), an effect believed to contribute to its beneficial cardiometabolic effects. OBJECTIVE: To validate the beneficial GLP-1 mediated cardiometabolic effects post VSG using GLP-1 antagoni...

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Detalles Bibliográficos
Autores principales: Kumar, Sunil, Lau, Raymond, Palaia, Thomas, Hall, Christopher, Lee, Jenny, Hall, Keneth, Brathwaite, Collin E., Ragolia, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123065/
https://www.ncbi.nlm.nih.gov/pubmed/27900077
http://dx.doi.org/10.1016/j.amsu.2016.11.007