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ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins

Exosomes are vesicles secreted to the extracellular environment through fusion with the plasma membrane of specific endosomes called multivesicular bodies (MVB) and mediate cell-to-cell communication in many biological processes. Posttranslational modifications are involved in the sorting of specifi...

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Detalles Bibliográficos
Autores principales: Villarroya-Beltri, Carolina, Baixauli, Francesc, Mittelbrunn, María, Fernández-Delgado, Irene, Torralba, Daniel, Moreno-Gonzalo, Olga, Baldanta, Sara, Enrich, Carlos, Guerra, Susana, Sánchez-Madrid, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123068/
https://www.ncbi.nlm.nih.gov/pubmed/27882925
http://dx.doi.org/10.1038/ncomms13588