The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization

Vascular permeability and neovascularization are implicated in many diseases including retinopathies and diabetic wound healing. Robo4 is an endothelial-specific transmembrane receptor that stabilizes the vasculature, as shown in Robo4(−/−) mice that develop hyperpermeability, but how Robo4 signals...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Prahst, Claudia, Mathivet, Thomas, Pibouin-Fragner, Laurence, Zhang, Jiasheng, Genet, Gael, Tong, Raymond, Dubrac, Alexandre, Eichmann, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123080/
https://www.ncbi.nlm.nih.gov/pubmed/27882935
http://dx.doi.org/10.1038/ncomms13517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123080/
https://www.ncbi.nlm.nih.gov/pubmed/27882935
http://dx.doi.org/10.1038/ncomms13517

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