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The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
Vascular permeability and neovascularization are implicated in many diseases including retinopathies and diabetic wound healing. Robo4 is an endothelial-specific transmembrane receptor that stabilizes the vasculature, as shown in Robo4(−/−) mice that develop hyperpermeability, but how Robo4 signals...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123080/ https://www.ncbi.nlm.nih.gov/pubmed/27882935 http://dx.doi.org/10.1038/ncomms13517 |