Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop

OBJECTIVE: Carbohydrate-response element-binding protein (ChREBP) is the major transcription factor conferring glucose-induced gene expression in pancreatic islets, liver and adipose tissue. Recently, a novel ChREBP isoform, ChREBP-β, was identified in adipose tissue and found to be also expressed i...

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Detalles Bibliográficos
Autores principales: Jing, Gu, Chen, Junqin, Xu, Guanlan, Shalev, Anath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123192/
https://www.ncbi.nlm.nih.gov/pubmed/27900263
http://dx.doi.org/10.1016/j.molmet.2016.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123192/
https://www.ncbi.nlm.nih.gov/pubmed/27900263
http://dx.doi.org/10.1016/j.molmet.2016.09.010

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