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Fab glycosylation of immunoglobulin G does not associate with improvement of rheumatoid arthritis during pregnancy

BACKGROUND: Changes in immunoglobulin G (IgG) constant domain (Fc) glycosylation are associated with changes in rheumatoid arthritis (RA) disease activity in response to pregnancy. Here, we sought to determine whether the same holds true for variable domain (Fab) glycosylation. METHODS: IgGs were ca...

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Detalles Bibliográficos
Autores principales: Bondt, Albert, Wuhrer, Manfred, Kuijper, T. Martijn, Hazes, Johanna M. W., Dolhain, Radboud J. E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123206/
https://www.ncbi.nlm.nih.gov/pubmed/27887659
http://dx.doi.org/10.1186/s13075-016-1172-1