Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management

BACKGROUND: Amplicon-based targeted resequencing is a commonly adopted solution for next-generation sequencing applications focused on specific genomic regions. The reliability of such approaches rests on the high specificity and deep coverage, although sequencing artifacts attributable to PCR-like...

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Detalles Bibliográficos
Autores principales: Zucca, Susanna, Villaraggia, Margherita, Gagliardi, Stella, Grieco, Gaetano Salvatore, Valente, Marialuisa, Cereda, Cristina, Magni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123238/
https://www.ncbi.nlm.nih.gov/pubmed/28185542
http://dx.doi.org/10.1186/s12859-016-1189-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123238/
https://www.ncbi.nlm.nih.gov/pubmed/28185542
http://dx.doi.org/10.1186/s12859-016-1189-0

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