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Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management
BACKGROUND: Amplicon-based targeted resequencing is a commonly adopted solution for next-generation sequencing applications focused on specific genomic regions. The reliability of such approaches rests on the high specificity and deep coverage, although sequencing artifacts attributable to PCR-like...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123238/ https://www.ncbi.nlm.nih.gov/pubmed/28185542 http://dx.doi.org/10.1186/s12859-016-1189-0 |