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variancePartition: interpreting drivers of variation in complex gene expression studies

BACKGROUND: As large-scale studies of gene expression with multiple sources of biological and technical variation become widely adopted, characterizing these drivers of variation becomes essential to understanding disease biology and regulatory genetics. RESULTS: We describe a statistical and visual...

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Detalles Bibliográficos
Autores principales: Hoffman, Gabriel E., Schadt, Eric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123296/
https://www.ncbi.nlm.nih.gov/pubmed/27884101
http://dx.doi.org/10.1186/s12859-016-1323-z