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A framework: make it useful to guide and improve practice of clinical trial design in smaller populations
The increased attention to design and analysis of randomised clinical trials in small populations has triggered thinking regarding the most appropriate design methods for a particular clinical research question. Decision schemes and algorithms have been proposed, with varying starting points and foc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123315/ https://www.ncbi.nlm.nih.gov/pubmed/27884148 http://dx.doi.org/10.1186/s12916-016-0752-x |