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Hyaluronan synthase 2 expressed by cancer-associated fibroblasts promotes oral cancer invasion

BACKGROUND: Hyaluronan synthases (HAS) control the biosynthesis of hyaluronan (HA) and critically modulate the tumor microenviroment. Cancer-associated fibroblasts (CAFs) affect the progression of a tumor by remolding the matrix. However, little is known about the role of HAS from CAFs in this proce...

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Detalles Bibliográficos
Autores principales: Zhang, Ziwen, Tao, Detao, Zhang, Ping, Liu, Xue, Zhang, Yuchao, Cheng, Jie, Yuan, Hua, Liu, Laikui, Jiang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123319/
https://www.ncbi.nlm.nih.gov/pubmed/27884164
http://dx.doi.org/10.1186/s13046-016-0458-0