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Hyaluronan synthase 2 expressed by cancer-associated fibroblasts promotes oral cancer invasion
BACKGROUND: Hyaluronan synthases (HAS) control the biosynthesis of hyaluronan (HA) and critically modulate the tumor microenviroment. Cancer-associated fibroblasts (CAFs) affect the progression of a tumor by remolding the matrix. However, little is known about the role of HAS from CAFs in this proce...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123319/ https://www.ncbi.nlm.nih.gov/pubmed/27884164 http://dx.doi.org/10.1186/s13046-016-0458-0 |