Cargando…

KAOS: a new automated computational method for the identification of overexpressed genes

BACKGROUND: Kinase over-expression and activation as a consequence of gene amplification or gene fusion events is a well-known mechanism of tumorigenesis. The search for novel rearrangements of kinases or other druggable genes may contribute to understanding the biology of cancerogenesis, as well as...

Descripción completa

Detalles Bibliográficos
Autores principales: Nuzzo, Angelo, Carapezza, Giovanni, Di Bella, Sebastiano, Pulvirenti, Alfredo, Isacchi, Antonella, Bosotti, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123341/
https://www.ncbi.nlm.nih.gov/pubmed/28185541
http://dx.doi.org/10.1186/s12859-016-1188-1