How do you design randomised trials for smaller populations? A framework

How should we approach trial design when we can get some, but not all, of the way to the numbers required for a randomised phase III trial? We present an ordered framework for designing randomised trials to address the problem when the ideal sample size is considered larger than the number of partic...

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Detalles Bibliográficos
Autores principales: Parmar, Mahesh K. B., Sydes, Matthew R., Morris, Tim P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123370/
https://www.ncbi.nlm.nih.gov/pubmed/27884190
http://dx.doi.org/10.1186/s12916-016-0722-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123370/
https://www.ncbi.nlm.nih.gov/pubmed/27884190
http://dx.doi.org/10.1186/s12916-016-0722-3

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