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How do you design randomised trials for smaller populations? A framework
How should we approach trial design when we can get some, but not all, of the way to the numbers required for a randomised phase III trial? We present an ordered framework for designing randomised trials to address the problem when the ideal sample size is considered larger than the number of partic...
Autores principales: | Parmar, Mahesh K. B., Sydes, Matthew R., Morris, Tim P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123370/ https://www.ncbi.nlm.nih.gov/pubmed/27884190 http://dx.doi.org/10.1186/s12916-016-0722-3 |
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