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SPECtre: a spectral coherence-­based classifier of actively translated transcripts from ribosome profiling sequence data

BACKGROUND: Active protein translation can be assessed and measured using ribosome profiling sequencing strategies. Prevailing analytical approaches applied to this technology make use of sequence fragment length profiling or reading frame occupancy enrichment to differentiate between active transla...

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Detalles Bibliográficos
Autores principales: Chun, Sang Y., Rodriguez, Caitlin M., Todd, Peter K., Mills, Ryan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123373/
https://www.ncbi.nlm.nih.gov/pubmed/27884106
http://dx.doi.org/10.1186/s12859-016-1355-4