Reconstruction of ancestral RNA sequences under multiple structural constraints

BACKGROUND: Secondary structures form the scaffold of multiple sequence alignment of non-coding RNA (ncRNA) families. An accurate reconstruction of ancestral ncRNAs must use this structural signal. However, the inference of ancestors of a single ncRNA family with a single consensus structure may bia...

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Detalles Bibliográficos
Autores principales: Tremblay-Savard, Olivier, Reinharz, Vladimir, Waldispühl, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123390/
https://www.ncbi.nlm.nih.gov/pubmed/28185557
http://dx.doi.org/10.1186/s12864-016-3105-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123390/
https://www.ncbi.nlm.nih.gov/pubmed/28185557
http://dx.doi.org/10.1186/s12864-016-3105-4

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