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Reconstruction of ancestral RNA sequences under multiple structural constraints
BACKGROUND: Secondary structures form the scaffold of multiple sequence alignment of non-coding RNA (ncRNA) families. An accurate reconstruction of ancestral ncRNAs must use this structural signal. However, the inference of ancestors of a single ncRNA family with a single consensus structure may bia...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123390/ https://www.ncbi.nlm.nih.gov/pubmed/28185557 http://dx.doi.org/10.1186/s12864-016-3105-4 |