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Characterization and management of long runs of homozygosity in parental nucleus lines and their associated crossbred progeny

BACKGROUND: In nucleus populations, regions of the genome that have a high frequency of runs of homozygosity (ROH) occur and are associated with a reduction in genetic diversity, as well as adverse effects on fitness. It is currently unclear whether, and to what extent, ROH stretches persist in the...

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Detalles Bibliográficos
Autores principales: Howard, Jeremy T., Tiezzi, Francesco, Huang, Yijian, Gray, Kent A., Maltecca, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123398/
https://www.ncbi.nlm.nih.gov/pubmed/27884108
http://dx.doi.org/10.1186/s12711-016-0269-y