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Anti-LRP/LR-specific antibody IgG1-iS18 impedes adhesion and invasion of pancreatic cancer and neuroblastoma cells

BACKGROUND: Cancer has become a global burden due to its high incidence and mortality rates, with an estimated 14.1 million cancer cases reported worldwide in 2012 particularly as a result of metastasis. Metastasis involves two crucial steps: adhesion and invasion, and the non-integrin receptor; the...

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Detalles Bibliográficos
Autores principales: Rebelo, Thalia M., Chetty, Carryn J., Ferreira, Eloise, Weiss, Stefan F. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123428/
https://www.ncbi.nlm.nih.gov/pubmed/27884119
http://dx.doi.org/10.1186/s12885-016-2953-2