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How Zn can impede Cu detoxification by chelating agents in Alzheimer's disease: a proof-of-concept study
The role of Cu and Zn ions in Alzheimer's disease is linked to the consequences of their coordination to the amyloid-β (Aβ) peptide, i.e. to the modulation of Aβ aggregation and to the production of Reactive Oxygen Species (ROS), two central events of the so-called amyloid cascade. The role of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123634/ https://www.ncbi.nlm.nih.gov/pubmed/27711738 http://dx.doi.org/10.1039/c6dt02308h |