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How Zn can impede Cu detoxification by chelating agents in Alzheimer's disease: a proof-of-concept study

The role of Cu and Zn ions in Alzheimer's disease is linked to the consequences of their coordination to the amyloid-β (Aβ) peptide, i.e. to the modulation of Aβ aggregation and to the production of Reactive Oxygen Species (ROS), two central events of the so-called amyloid cascade. The role of...

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Detalles Bibliográficos
Autores principales:	Conte-Daban, Amandine, Day, Adam, Faller, Peter, Hureau, Christelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123634/ https://www.ncbi.nlm.nih.gov/pubmed/27711738 http://dx.doi.org/10.1039/c6dt02308h

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