Tuning the metabolism of the anticancer drug cisplatin with chemoprotective agents to improve its safety and efficacy

Numerous in vivo studies have shown that the severe toxic side-effects of intravenously administered cisplatin can be significantly reduced by the co-administration of sulfur-containing ‘chemoprotective agents’. Using a metallomics approach, a likely biochemical basis for these potentially useful ob...

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Detalles Bibliográficos
Autores principales: Sooriyaarachchi, Melani, George, Graham N., Pickering, Ingrid J., Narendran, Aru, Gailer, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123636/
https://www.ncbi.nlm.nih.gov/pubmed/27722429
http://dx.doi.org/10.1039/c6mt00183a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123636/
https://www.ncbi.nlm.nih.gov/pubmed/27722429
http://dx.doi.org/10.1039/c6mt00183a

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