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Tuning the metabolism of the anticancer drug cisplatin with chemoprotective agents to improve its safety and efficacy
Numerous in vivo studies have shown that the severe toxic side-effects of intravenously administered cisplatin can be significantly reduced by the co-administration of sulfur-containing ‘chemoprotective agents’. Using a metallomics approach, a likely biochemical basis for these potentially useful ob...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123636/ https://www.ncbi.nlm.nih.gov/pubmed/27722429 http://dx.doi.org/10.1039/c6mt00183a |