Valproic acid protects against haemorrhagic shock‐induced signalling changes via PPARγ activation in an in vitro model

BACKGROUND AND PURPOSE: Valproic acid (VPA), a widely used epilepsy and bipolar disorder treatment, provides acute protection against haemorrhagic shock‐induced mortality in a range of in vivo models through an unknown mechanism. In the liver, this effect occurs with a concomitant protection against...

Descripción completa

Detalles Bibliográficos
Autores principales: Zuckermann, Alexandra M E, La Ragione, Roberto M, Baines, Deborah L, Williams, Robin S B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123713/
https://www.ncbi.nlm.nih.gov/pubmed/26333042
http://dx.doi.org/10.1111/bph.13320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123713/
https://www.ncbi.nlm.nih.gov/pubmed/26333042
http://dx.doi.org/10.1111/bph.13320

Ejemplares similares