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Valproic acid protects against haemorrhagic shock‐induced signalling changes via PPARγ activation in an in vitro model

BACKGROUND AND PURPOSE: Valproic acid (VPA), a widely used epilepsy and bipolar disorder treatment, provides acute protection against haemorrhagic shock‐induced mortality in a range of in vivo models through an unknown mechanism. In the liver, this effect occurs with a concomitant protection against...

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Detalles Bibliográficos
Autores principales:	Zuckermann, Alexandra M E, La Ragione, Roberto M, Baines, Deborah L, Williams, Robin S B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123713/ https://www.ncbi.nlm.nih.gov/pubmed/26333042 http://dx.doi.org/10.1111/bph.13320

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