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Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero

BACKGROUND: Children exposed to maternal smoking during pregnancy exhibit increased risk for many adverse health effects. Maternal smoking influences methylation in newborns at specific CpG sites (CpGs). Here, we extend evaluation of individual CpGs to gene-level and pathway-level analyses among 106...

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Detalles Bibliográficos
Autores principales: Rotroff, Daniel M., Joubert, Bonnie R., Marvel, Skylar W., Håberg, Siri E., Wu, Michael C., Nilsen, Roy M., Ueland, Per M., Nystad, Wenche, London, Stephanie J., Motsinger-Reif, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124223/
https://www.ncbi.nlm.nih.gov/pubmed/27887572
http://dx.doi.org/10.1186/s12864-016-3310-1