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Outcomes of high-dose levofloxacin therapy remain bound to the levofloxacin minimum inhibitory concentration in complicated urinary tract infections

BACKGROUND: Fluoroquinolones are a guideline-recommended therapy for complicated urinary tract infections, including pyelonephritis. Elevated drug concentrations of fluoroquinolones in the urine and therapy with high-dose levofloxacin are believed to overcome resistance and effectively treat infecti...

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Detalles Bibliográficos
Autores principales: Armstrong, Eliana S., Mikulca, Janelle A., Cloutier, Daniel J., Bliss, Caleb A., Steenbergen, Judith N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124239/
https://www.ncbi.nlm.nih.gov/pubmed/27887579
http://dx.doi.org/10.1186/s12879-016-2057-2