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In-vitro function of upstream visfatin polymorphisms that are associated with adverse cardiometabolic parameters in obese children

BACKGROUND: Visfatin is an adipokine associated with glucose and lipid metabolism. We previously reported two visfatin upstream single nucleotide polymorphisms (SNPs), c.-3187G > A (rs11977021) and c.-1537C > T (rs61330082), which were in perfect linkage disequilibrium, in a Singaporean cohort...

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Detalles Bibliográficos
Autores principales: Ooi, Delicia Shu Qin, Ong, Siong Gim, Heng, Chew Kiat, Loke, Kah Yin, Lee, Yung Seng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124300/
https://www.ncbi.nlm.nih.gov/pubmed/27887573
http://dx.doi.org/10.1186/s12864-016-3315-9