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Immune modulation of CD4(+)CD25(+) regulatory T cells by zoledronic acid

BACKGROUND: CD4(+)CD25(+) regulatory T (Treg) cells suppress tumor immunity by inhibiting immune cells. Manipulation of Treg cells represents a new strategy for cancer treatment. Zoledronic acid (ZA), a nitrogen-containing bisphosphonate, inhibits the expression of receptor activator of nuclear fact...

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Detalles Bibliográficos
Autores principales: Liu, Hsien, Wang, Shih-Han, Chen, Shin-Cheh, Chen, Ching-Ying, Lo, Jo-Lin, Lin, Tsun-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124310/
https://www.ncbi.nlm.nih.gov/pubmed/27887569
http://dx.doi.org/10.1186/s12865-016-0183-7