LBSizeCleav: improved support vector machine (SVM)-based prediction of Dicer cleavage sites using loop/bulge length

BACKGROUND: Dicer is necessary for the process of mature microRNA (miRNA) formation because the Dicer enzyme cleaves pre-miRNA correctly to generate miRNA with correct seed regions. Nonetheless, the mechanism underlying the selection of a Dicer cleavage site is still not fully understood. To date, s...

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Detalles Bibliográficos
Autores principales: Bao, Yu, Hayashida, Morihiro, Akutsu, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124314/
https://www.ncbi.nlm.nih.gov/pubmed/27887571
http://dx.doi.org/10.1186/s12859-016-1353-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124314/
https://www.ncbi.nlm.nih.gov/pubmed/27887571
http://dx.doi.org/10.1186/s12859-016-1353-6

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