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Application of the marginal structural model to account for suboptimal adherence in a randomized controlled trial

BACKGROUND: There is considerable interest in adjusting for suboptimal adherence in randomized controlled trials. A per-protocol analysis, for example removes individuals who fail to achieve a minimal level of adherence. One can also reassign non-adherers to the control group, censor them at the poi...

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Detalles Bibliográficos
Autores principales: Rochon, James, Bhapkar, Manjushri, Pieper, Carl F., Kraus, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124349/
https://www.ncbi.nlm.nih.gov/pubmed/27900372
http://dx.doi.org/10.1016/j.conctc.2016.10.005