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Increased mitochondrial superoxide in the brain, but not periphery, sensitizes mice to angiotensin II-mediated hypertension
Angiotensin II (AngII) elicits the production of superoxide (O(2)(•−)) from mitochondria in numerous cell types within peripheral organs and in the brain suggesting a role for mitochondrial-produced O(2)(•−) in the pathogenesis of hypertension. However, it remains unclear if mitochondrial O(2)(•−) i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124355/ https://www.ncbi.nlm.nih.gov/pubmed/27889641 http://dx.doi.org/10.1016/j.redox.2016.11.011 |