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PLK1, A Potential Target for Cancer Therapy

Polo-like kinase 1 (PLK1) plays an important role in the initiation, maintenance, and completion of mitosis. Dysfunction of PLK1 may promote cancerous transformation and drive its progression. PLK1 overexpression has been found in a variety of human cancers and was associated with poor prognoses in...

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Detalles Bibliográficos
Autores principales: Liu, Zhixian, Sun, Qingrong, Wang, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124362/
https://www.ncbi.nlm.nih.gov/pubmed/27888710
http://dx.doi.org/10.1016/j.tranon.2016.10.003