Targeted Inhibition of the miR-199a/214 Cluster by CRISPR Interference Augments the Tumor Tropism of Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Hypoxic Condition

The human induced pluripotent stem cell (hiPSC) provides a breakthrough approach that helps overcoming ethical and allergenic challenges posed in application of neural stem cells (NSCs) in targeted cancer gene therapy. However, the tumor-tropic capacity of hiPSC-derived NSCs (hiPS-NSCs) still has mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Yumei, Xu, Xuehu, An, Xiuli, Sun, Xiaofang, Wang, Shu, Zhu, Detu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124688/
https://www.ncbi.nlm.nih.gov/pubmed/27965712
http://dx.doi.org/10.1155/2016/3598542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124688/
https://www.ncbi.nlm.nih.gov/pubmed/27965712
http://dx.doi.org/10.1155/2016/3598542

Ejemplares similares