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Blood Plasma of Patients with Parkinson's Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity

A pathological hallmark of Parkinson's disease (PD) is formation of Lewy bodies in neurons of the brain. This has been attributed to the spread of α-synuclein (α-syn) aggregates, which involves release of α-syn from a neuron and its reuptake by a neighboring neuron. We found that treatment with...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Li, Xin, Li, Xuran, Yang, Weiwei, Yu, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124690/
https://www.ncbi.nlm.nih.gov/pubmed/27965913
http://dx.doi.org/10.1155/2016/7596482