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Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases
The human complement factor H-related protein-3 (FHR-3) is a soluble regulator of the complement system. Homozygous cfhr3/1 deletion is a genetic risk factor for the autoimmune form of atypical hemolytic-uremic syndrome (aHUS), while also found to be protective in age-related macular degeneration (A...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124756/ https://www.ncbi.nlm.nih.gov/pubmed/27965669 http://dx.doi.org/10.3389/fimmu.2016.00542 |