Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines

Gene silencing by small interfering RNA (siRNA) is useful for analyzing the functions of human immune cells. However, the transfection of siRNA to human immune cells is difficult. Here, we used a multifunctional envelope-type nanodevice (MEND) containing YSK12-C4 (YSK12-MEND) to efficiently introduc...

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Detalles Bibliográficos
Autores principales: Nakamura, Takashi, Kuroi, Moeka, Fujiwara, Yuki, Warashina, Shota, Sato, Yusuke, Harashima, Hideyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124971/
https://www.ncbi.nlm.nih.gov/pubmed/27892533
http://dx.doi.org/10.1038/srep37849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124971/
https://www.ncbi.nlm.nih.gov/pubmed/27892533
http://dx.doi.org/10.1038/srep37849

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