Cargando…
Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines
Gene silencing by small interfering RNA (siRNA) is useful for analyzing the functions of human immune cells. However, the transfection of siRNA to human immune cells is difficult. Here, we used a multifunctional envelope-type nanodevice (MEND) containing YSK12-C4 (YSK12-MEND) to efficiently introduc...
Autores principales: | Nakamura, Takashi, Kuroi, Moeka, Fujiwara, Yuki, Warashina, Shota, Sato, Yusuke, Harashima, Hideyoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124971/ https://www.ncbi.nlm.nih.gov/pubmed/27892533 http://dx.doi.org/10.1038/srep37849 |
Ejemplares similares
-
The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy
por: Endo, Rikito, et al.
Publicado: (2019) -
Novel PEGylated Lipid Nanoparticles Have a High Encapsulation Efficiency and Effectively Deliver MRTF-B siRNA in Conjunctival Fibroblasts
por: Sanghani, Amisha, et al.
Publicado: (2021) -
Optimization of a siRNA Carrier Modified with a pH-Sensitive Cationic Lipid and a Cyclic RGD Peptide for Efficiently Targeting Tumor Endothelial Cells
por: Hada, Tomoya, et al.
Publicado: (2015) -
Evolution of drug delivery system from viewpoint of controlled intracellular trafficking and selective tissue targeting toward future nanomedicine
por: Yamada, Yuma, et al.
Publicado: (2020) -
Development of the iLiNP Device: Fine Tuning the Lipid
Nanoparticle Size within 10 nm for Drug Delivery
por: Kimura, Niko, et al.
Publicado: (2018)