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Mitochondrial fat oxidation is essential for lipid-induced inflammation in skeletal muscle in mice

Inflammation, lipotoxicity and mitochondrial dysfunction have been implicated in the pathogenesis of obesity-induced insulin resistance and type 2 diabetes. However, how these factors are intertwined in the development of obesity/insulin resistance remains unclear. Here, we examine the role of mitoc...

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Detalles Bibliográficos
Autores principales: Warfel, Jaycob D., Bermudez, Estrellita M., Mendoza, Tamra M., Ghosh, Sujoy, Zhang, Jingying, Elks, Carrie M., Mynatt, Randall, Vandanmagsar, Bolormaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124994/
https://www.ncbi.nlm.nih.gov/pubmed/27892502
http://dx.doi.org/10.1038/srep37941