Pancreatic Mesenchyme Regulates Islet Cellular Composition in a Patched/Hedgehog-Dependent Manner

Pancreas development requires restrained Hedgehog (Hh) signaling activation. While deregulated Hh signaling in the pancreatic mesenchyme has been long suggested to be detrimental for proper organogenesis, this association was not directly shown. Here, we analyzed the contribution of mesenchymal Hh s...

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Detalles Bibliográficos
Autores principales: Hibsher, Daniel, Epshtein, Alona, Oren, Nufar, Landsman, Limor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125096/
https://www.ncbi.nlm.nih.gov/pubmed/27892540
http://dx.doi.org/10.1038/srep38008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125096/
https://www.ncbi.nlm.nih.gov/pubmed/27892540
http://dx.doi.org/10.1038/srep38008

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