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Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes

Recent studies have shown that circular RNAs (circRNAs) are abundant, widely expressed in mammals, and can display cell-type specific expression. However, how production of circRNAs is regulated and their precise biological function remains largely unknown. To study how circRNAs might be regulated d...

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Detalles Bibliográficos
Autores principales: Dou, Yongchao, Cha, Diana J., Franklin, Jeffrey L., Higginbotham, James N., Jeppesen, Dennis K., Weaver, Alissa M., Prasad, Nripesh, Levy, Shawn, Coffey, Robert J., Patton, James G., Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125100/
https://www.ncbi.nlm.nih.gov/pubmed/27892494
http://dx.doi.org/10.1038/srep37982