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Macromolecular Crowding Regulates the Gene Expression Profile by Limiting Diffusion
We seek to elucidate the role of macromolecular crowding in transcription and translation. It is well known that stochasticity in gene expression can lead to differential gene expression and heterogeneity in a cell population. Recent experimental observations by Tan et al. have improved our understa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125560/ https://www.ncbi.nlm.nih.gov/pubmed/27893768 http://dx.doi.org/10.1371/journal.pcbi.1005122 |