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Macromolecular Crowding Regulates the Gene Expression Profile by Limiting Diffusion

We seek to elucidate the role of macromolecular crowding in transcription and translation. It is well known that stochasticity in gene expression can lead to differential gene expression and heterogeneity in a cell population. Recent experimental observations by Tan et al. have improved our understa...

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Detalles Bibliográficos
Autores principales:	Golkaram, Mahdi, Hellander, Stefan, Drawert, Brian, Petzold, Linda R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125560/ https://www.ncbi.nlm.nih.gov/pubmed/27893768 http://dx.doi.org/10.1371/journal.pcbi.1005122

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