Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1

Kaposi’s sarcoma-associated herpesvirus (KSHV), the causative agent of Kaposi’s sarcoma, encodes 25 mature viral miRNAs. MCP-1-induced protein-1 (MCPIP1), a critical regulator of immune homeostasis, has been shown to suppress miRNA biosynthesis via cleavage of precursor miRNAs through its RNase doma...

Descripción completa

Detalles Bibliográficos
Autores principales: Happel, Christine, Ramalingam, Dhivya, Ziegelbauer, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125562/
https://www.ncbi.nlm.nih.gov/pubmed/27893764
http://dx.doi.org/10.1371/journal.pbio.2000998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125562/
https://www.ncbi.nlm.nih.gov/pubmed/27893764
http://dx.doi.org/10.1371/journal.pbio.2000998

Ejemplares similares