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Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1

Kaposi’s sarcoma-associated herpesvirus (KSHV), the causative agent of Kaposi’s sarcoma, encodes 25 mature viral miRNAs. MCP-1-induced protein-1 (MCPIP1), a critical regulator of immune homeostasis, has been shown to suppress miRNA biosynthesis via cleavage of precursor miRNAs through its RNase doma...

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Detalles Bibliográficos
Autores principales:	Happel, Christine, Ramalingam, Dhivya, Ziegelbauer, Joseph M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125562/ https://www.ncbi.nlm.nih.gov/pubmed/27893764 http://dx.doi.org/10.1371/journal.pbio.2000998

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